Adrenal disorders are often difficult to diagnose due to common symptoms, and challenging to treat due to common comorbidities. Adrenal Disorders: 100 Cases from the Adrenal Clinic provides a comprehensive, case-based approach to the evaluation and treatment of both common and uncommon adrenal disorders, offering practical, real-world guidance highlighted by detailed laboratory evaluations, computed cross sectional images, nuclear medicine images, and gross pathology photographs.
Key Features
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Features 100 two-page cases covering a wide range of common and uncommon adrenal disorders.
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Includes case report, investigations, treatment, and outcome for each case, plus a case overview with expert advice, take-home points, and references.
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Organizes comprehensive content by type of disorder, including adrenal masses (benign and malignant), primary aldosteronism, ACTH-independent Cushing syndrome, ACTH-dependent Cushing syndrome, adrenal carcinoma, pheochromocytoma, adrenal and ovarian hyperandrogenism, and adrenal disorders in pregnancy.
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Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Author Information
By William F. Young, MD, Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Tyson Family Endocrinology Clinical Professor; Professor of Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota and Irina Bancos, MD, Associate Professor, Division of Endocrinology and Metabolism at the Mayo Clinic, Rochester, Minnesota
Section A. Incidentally Discovered Adrenal Mass
Case #1: 45-Year Old Woman with an Incidentally Discovered Large Adrenal Mass
Case #2: Adrenal Mass in a Patient with History of Extra-adrenal Malignancy: the Role of Imaging
Case #3: Incidentally Discovered Adrenal Mass in a Patient with History of Extra-adrenal Malignancy: the Role of Adrenal Biopsy
Case #4: Nonfunctioning Lipid Rich Adrenocortical Adenoma—Role of Follow-up
Case #5: 54-Year Old Woman with an Incidentally Discovered Adrenal Mass and Abnormal Dexamethasone Suppression Test: Role of Adrenalectomy
Case #6: Lipid Poor Adrenal Masses—The Case for Aggressive Management
Section B. Primary Aldosteronism
Case #7: Primary Aldosteronism—When Adrenal Venous Sampling is not Needed Before Unilateral Adrenalectomy
Case #8: Primary Aldosteronism with Unilateral Adrenal Nodule on Computed Tomography
Case #9: Primary Aldosteronism with Bilateral Adrenal Nodules on Computed Tomography
Case #10: Primary Aldosteronism Caused by Unilateral Adrenal Hyperplasia
Case #11: Primary Aldosteronism in a Patient with Bilateral Macronodular Adrenal Hyperplasia and Associated Clinically Important Cortisol Co-secretion
Case #12: Primary Aldosteronism in a Patient with an Adrenal Macroadenoma and Clinically Important Cortisol Co-secretion
Case #13: Primary Aldosteronism in a Patient Treated with Spironolactone
Case #14: Failed Catheterization of the Right Adrenal Vein—When Incomplete Adrenal Venous Sampling Data Can Be Used to Direct a Surgical Cure
Case #15: Primary Aldosteronism: When Adrenal Venous Sampling Shows Suppressed Aldosterone Secretion From Both Adrenal Glands
Section C. ACTH-Independent Cushing Syndrome
Case #16: 28-Year-Old Woman with Remote History of Adrenal Mass Presenting with New Onset Hypertension and Weight Gain
Case #17: 26-Year-Old Woman with a Discrepant Work-up for Cushing Syndrome Subtype
Case #18: 45-Year-Old Woman with Corticotropin-Independent Cushing Syndrome and Bilateral Adrenal Adenomas
Case #19: Corticotropin-Independent Cushing Syndrome in a Patient with “Normal Adrenal Imaging
Case #20: 66-Year-Old Woman with Corticotropin-Independent Hypercortisolism and Bilateral Macronodular Adrenal Hyperplasia
Case #21: 35-Year-Old Woman with Low Bone Density and Fractures
Case #22: Carney Triad (Pentad) and Adrenal Adenoma with Clinically Important Cortisol Secretory Autonomy
Section D. Adrenal Cortical Carcinoma and Oncocytic Neoplasm
Case #23: Adrenal cortical carcinoma in a patient with history of adrenal incidentaloma
Case #24: Unexpected Diagnosis of Adrenal Cortical Carcinoma: Role of Urinary Steroid Profiling
Case #25: Oncocytic adrenocortical carcinoma
Case #26: Mitotane therapy in the ENSAT Stage II Adrenocortical Carcinoma
Case #27: Cortisol-Secreting Metastatic Adrenocortical Carcinoma—Role for Surgical Debulking of the Primary Tumor
Case #28: Adrenocortical Carcinoma and Severe Cushing Syndrome
Case #29: Pure Aldosterone-Secreting Adrenocortical Carcinoma
Case #30: Long-standing Primary Aldosteronism in a Patient Diagnosed with Metastatic Adrenocortical Carcinoma
Case #31: Adrenocortical Carcinoma Associated with Lynch Syndrome
Case #32: Adrenocortical Carcinoma Associated with Multiple Endocrine Neoplasia Type 1
Case #33: Adrenocortical Carcinoma Presenting with Inferior Vena Cava Thrombus
Case #34: Management of Mitotane Therapy in Adrenocortical Carcinoma
Section E. Pheochromocytoma and Paraganglioma
Case #35: Most Pheochromocytomas Grow Slowly
Case #36: The “Prebiochemical Pheochromocytoma
Case #37: Huge Catecholamine-Secreting Tumor
Case#38: Metyrosine Use in a Patient with Metastatic Pheochromocytoma
Case #39: Pheochromocytoma in a Patient with Neurofibromatosis Type 1
Case #40: New Diagnosis of Multiple Endocrine Neoplasia Type 2A in a Patient with Bilateral Pheochromocytomas
Case #41: Pheochromocytoma in a Patient with von Hippel Lindau Disease
Case #42: Bilateral Pheochromocytoma in a Patient with MYC-associated Protein X (MAX) Genetic Predisposition
Case #43: The Cystic Pheochromocytoma
Case #44: Skull Base and Neck Paragangliomas—Considerations for the Endocrinologist
Case #45: Cardiac Paraganglioma.
Case #46: Pheochromocytoma in Multiple Endocrine Neoplasia Type 2B
Case #47: Metastatic Paraganglioma—An Approach to Management and the Use Serial Imaging to Assess Rate of Tumor Progression
Case #48: Metastatic Pheochromocytoma—Role for 68-Ga DOTATATE PET CT
Case #49: Carney Triad (Pentad) and Catecholamine-Secreting Paragangliomas
Case #50: Metastatic Paraganglioma—Role For Systemic Chemotherapy
Case #51: Cryoablation Therapy for Metastatic Paraganglioma
Case #52: Paraganglioma in a patient with cyanotic cardiac disease
Case #53: Metastatic Paraganglioma—Role For External Beam Radiation Therapy
Section F. Corticotropin (ACTH)-Dependent Hypercortisolism
Case #54:ACTH-Dependent Cushing Syndrome can be frequently misdiagnosed
Case #55: ACTH-Dependent Cushing Syndrome—Role for Inferior Petrosal Sinus Sampling
Case #56: ACTH-Dependent Cushing Syndrome—When Inferior Petrosal Sinus Sampling is Not Needed
Case #57: Severe ACTH-Dependent Cushing Syndrome Due to a Pituitary Adenoma
Ectopic Cushing Syndrome Associated with Multiple Endocrine Neoplasia Type 2B
Case #59: Ectopic Cushing Syndrome Treated with Cryoablation
Case #60: Cyclical Ectopic Cushing Syndrome
Case #61: Mild Cushing Syndrome Associated with Ectopic Corticotropin Secretion
Case #62: Bilateral Adrenal Cryoablation in Corticotropin-dependent Cushing Syndrome
Case #63: Cushing Syndrome Associated with Ectopic Corticotropin and Corticotropin Releasing Hormone Secreting Pheochromocytoma
Case #64: Cushing Syndrome in the Setting of Multiple Endocrine Neoplasia Type 1
Section G. Other Adrenal Masses
Case #65: Adrenal Myelolipoma—A Computed Tomography Diagnosis
Case #66: Adrenal Schwannoma
Case #67: Trauma-Related Unilateral Adrenal Hemorrhage
Case #68: Bilateral Adrenal Hemorrhage
Case #69: Primary Adrenal Teratoma
Case #70: The Adrenal Stone
Case #71: Simple Adrenal Cyst
Case #72: Adrenal Cystic Lymphangioma
Case #73: Adrenal Hemangioma
Case #74: Adrenal Ganglioneuroma
Case #75: 42-Year-Old Woman with a Large Adrenal Mass
Case #76: Primary Adrenal Leiomyosarcoma
Case #77: Primary Adrenal Lymphoma
Case #78. 39-Year-Old Man with a Large Adrenal Mass
Case # 79: 59-Year-Old Man with Enlarging Bilateral Adrenal Masses
Case # 80: 65-Year-Old Man with Primary Adrenal Insufficiency
Case #81: 47-Year-Old Man with Primary Adrenal Insufficiency
Case #82: Bilateral Adrenal Myelolipoma—Think of Congenital Adrenal Hyperplasia
Case #83: A Unilateral Lipid Poor Adrenal Mass—An Atypical Presentation of Adrenal Histoplasmosis
Case #84: Bilateral Macronodular Adrenal Hyperplasia (BMAH) in the Setting of Multiple Endocrine Neoplasia Type 1
Case #85: Pseudo-Adrenal Masses
Section H. Adrenal and Ovarian Hyperandrogenism
Case #86: A Huge Adrenal Myelolipoma in a Patient with a Suboptimally Controlled Congenital Adrenal Hyperplasia
Case #87: Balancing Glucocorticoid and Androgen Excess in Congenital Adrenal Hyperplasia
Case #88: Dehydroepiandrosterone-sulfate (DHEA-S): The “Love it or “Hate it Hormone
Case #89: Sorting out the Source of Androgen Excess in a Postmenopausal Woman with an Adrenal and an Ovarian Mass
Case #90: Primary Testosterone-Secreting Adrenocortical Carcinoma in a Premenopausal Woman.
Case #91: Premenopausal Woman with Testosterone-secreting Ovarian Tumor
Case #92: Sorting out the Source of Androgen Excess in a Postmenopausal Woman with an Adrenal Mass
Case #93: Testosterone-Secreting Benign Adrenal Adenoma in a Postmenopausal Woman
Section I. Adrenal Disorders in Pregnancy
Case #94: Malignant Pheochromocytoma in Pregnancy
Case #95: Catecholamine-Secreting Paraganglioma in Pregnancy
Case #96: The Peripartum Diagnosis of Pheochromocytoma and a Genetic Mystery Solved
Case #97. History of Pregnancy in a 41-Year-Old Woman with Undiagnosed Cushing syndrome
Case #98: Pregnancy in a Patient with Primary Adrenal Insufficiency
Case #99: Pregnancy in a Patient with 21-Hydroxylase Deficiency
Case #100: Primary Aldosteronism in Pregnancy
"This book provides practical guidance and clinical insight for the assessment and management of a wide variety of adrenal disorders using cased-based learning. It is a helpful resource for practitioners and trainees alike, especially for reviewing rarely seen cases with expert advice."
©Doody’s Review Service, 2022, Marcelo Ramirez, M.D. (Cook County Health)
